It is specifically convenient using Guix-the-system within a foreign distribution,
such as Debian, for development and tests. The package management
system can be used on top of the system, but I find it quite interesting to
explore the potential of the Guix distribution in the context of virtualized
environments. For personal use, that is also the ideal way to avoid breaking
your own daily boxes every couple of days with daredevil approaches to personal
computing.